Prof. Aralov Andrey | IBCH RAS | Russia
Prof. Aralov Andrey holds a PhD (2011) in the chemical synthesis of natural and modified oligonucleotides using the phosphotriester method and currently serves as the Head of the Group of Molecular Tools for Living System Studies at the Institute of Bioorganic Chemistry, Russian Academy of Sciences (since 2018). Since 2013, he has curated and executed multiple competitive grants funded by the Russian Scientific Foundation for Basic Research and the Russian Science Foundation, contributing extensively to innovations in nucleic acid chemistry, molecular tools, aptamers, pH-responsive sensors, antiviral nucleosides, red-light fluorescent systems, and genomic DNA i-motif technologies. He is the author of more than seventy publications indexed in Scopus and Web of Science, with a strong track record in high-impact journals including Nucleic Acids Research, Sensors and Actuators B: Chemical, Current Issues in Molecular Biology, ACS Sensors, Nature Communications, Biosensors and Bioelectronics, and others. His notable works span DNA aptamer architectures with high affinity for influenza A virus, diversification of i-motif-based pH sensors, advances in nucleoside antiviral mechanisms, Mango-based red-light RNA tracking systems, ratiometric i-motif long-term pH monitoring tools, mechanistic studies of oxidized DNA lesions, and cell-free prototyping strategies for therapeutic peptides and proteins. His research outputs have been cited 548 times across 396 documents, reflecting his significant impact in the fields of nucleic acid chemistry and molecular biosensing, with an h-index of 14. In addition to his research achievements, he has authored several postgraduate-level courses on nucleic acid chemistry, contributing to advanced scientific training in the field.
Featured Publications
Boldinova, E. O., Kruchinin, A. A., Kamzeeva, P. N., Aralov, A. V., & Makarova, A. V. (2025). Accurate DNA synthesis across 8-oxoadenine by human PrimPol. International Journal of Molecular Sciences, 26(14), 6796.
Kamzeeva, P. N., Alferova, V. A., Korshun, V. A., Varizhuk, A. M., & Aralov, A. V. (2025). 5′-UTR G-quadruplex-mediated translation regulation in eukaryotes: Current understanding and methodological challenges. International Journal of Molecular Sciences, 26(3), 1187.
Kruchinin, A. A., Kamzeeva, P. N., Zharkov, D. O., Aralov, A. V., & Makarova, A. V. (2024). 8-Oxoadenine: A “new” player of the oxidative stress in mammals? International Journal of Molecular Sciences, 25(2), 1342.
Kamzeeva, P., Dagaev, N., Lizunova, S., Khodarovich, Y., Sogomonyan, A., Kolchanova, A., Pokrovsky, V., Alferova, V., Chistov, A., Eshtukov-Shcheglov, A., et al. (2023). Synthesis and biological evaluation of benzo[4,5]- and naphtho[2′,1′:4,5]imidazo[1,2-c]pyrimidinone derivatives. Biomolecules, 13(11), 1669.
Knizhnik, E., Chumakov, S., Svetlova, J., Pavlova, I., Khodarovich, Y., Brylev, V., Severov, V., Alieva, R., Kozlovskaya, L., Andreev, D., et al. (2023). Unwinding the SARS-CoV-2 ribosomal frameshifting pseudoknot with LNA and G-clamp-modified phosphorothioate oligonucleotides inhibits viral replication. Biomolecules, 13(11), 1660.
Kamzeeva, P., Petushkov, I., Knizhnik, E., Snoeck, R., Khodarovich, Y., Ryabukhina, E., Alferova, V., Eshtukov-Shcheglov, A., Belyaev, E., Svetlova, J., et al. (2023). Phenotypic test of benzo[4,5]imidazo[1,2-c]pyrimidinone-based nucleoside and non-nucleoside derivatives against DNA and RNA viruses, including coronaviruses. International Journal of Molecular Sciences, 24(19), 14540.
Kamzeeva, P. N., Aralov, A. V., Alferova, V. A., & Korshun, V. A. (2023). Recent advances in molecular mechanisms of nucleoside antivirals. Current Issues in Molecular Biology, 45(8), 433.