Tokyo Teishin Hospital, Japan.
Prof. Tatsuya Yamasoba is a distinguished otologist and researcher specializing in hearing loss and otolaryngology. He currently serves as the Director of Tokyo Teishin Hospital and is Professor Emeritus at the University of Tokyo. With an extensive career in academia and clinical practice, he has made groundbreaking contributions to understanding and treating hearing loss. He previously chaired the Department of Otolaryngology at the University of Tokyo (2007–2023) and served as Vice Dean of the Faculty of Medicine (2017–2023). He is actively involved in international otology organizations and currently leads the Japanese Audiological Society.
Profile
🎓 Education
Prof. Tatsuya Yamasoba earned his Doctor of Medicine (M.D.) from the University of Tokyo in 1983, where he laid the foundation for his distinguished career in otology and hearing research. To further expand his expertise, he pursued a research fellowship at the Kresge Hearing Research Institute, University of Michigan (1996–1998). During this time, he conducted advanced studies on the pathophysiology of hearing loss, focusing on noise-induced and age-related auditory dysfunctions. His time at Michigan provided him with valuable insights into the molecular mechanisms of hearing loss, shaping his future contributions to otolaryngology and auditory neuroscience.
💼 Experience
Prof. Tatsuya Yamasoba is a highly esteemed leader in the field of otolaryngology, currently serving as the Director of Tokyo Teishin Hospital (2023–Present). He is also Professor Emeritus at the University of Tokyo, where he has made significant contributions to medical education and research. From 2017 to 2023, he held the position of Vice Dean of the Faculty of Medicine at the University of Tokyo, overseeing academic and clinical advancements.
Previously, he led the Department of Otolaryngology at the University of Tokyo (2007–2023), where he played a pivotal role in advancing hearing research and surgical innovations. His influence extends globally as an Executive Board Member of the International Federation of ORL Societies, Asia Oceania ORL-HNS, and ORL Society of Japan. Additionally, he currently serves as the President of the Japanese Audiological Society, driving forward research and clinical developments in audiology and hearing disorders.
🔬 Research Interests
Prof. Yamasoba's research focuses on the pathophysiology of hearing loss, particularly noise-induced hearing loss, age-related hearing loss, and vestibular dysfunction caused by mitochondrial DNA mutations. His work has identified oxidative stress and mitochondrial dysfunction as key factors in hearing disorders, leading to novel strategies for prevention and treatment. His current projects include:
Nanomicell-based Hair Cell Regeneration (Atoh1 mRNA & p27 siRNA therapy)
iPS Cell-Induced Regenerative Medicine for Sensory Organs
Nanomicellization of Chemotherapeutic Agents to Reduce Ototoxicity
🏆 Awards & Recognitions
Young Investigator Award, Japan Otological Society
Distinguished Researcher Award, Japanese Society of Otorhinolaryngology
Honorary President (2027), Asia Oceania ORL-HNS Congress
Collegium ORLAS President (2023)
📚 Selected Publications
1️⃣ Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
📄 Science (2005) | Cited by: 2,541
2️⃣ Novel Scoring System and Algorithm for Classifying Chronic Rhinosinusitis: The JESREC Study
📄 Allergy (2015) | Cited by: 675
3️⃣ Current Concepts in Age-Related Hearing Loss: Epidemiology and Mechanistic Pathways
📄 Hearing Research (2013) | Cited by: 674
4️⃣ Mechanisms of Noise-Induced Hearing Loss Indicate Multiple Methods of Prevention
📄 Hearing Research (2007) | Cited by: 528
5️⃣ Rational Design of Reversible Fluorescent Probes for Live-Cell Imaging and Quantification of Fast Glutathione Dynamics
📄 Journal (TBD)