Muhammad Younus | Biotechnology and Molecular Biology | Research Excellence Award

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Dauren Botbayev | Molecular Genetics | Research Excellence Award

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Dr. Dauren Botbayev | Molecular Genetics | Research Excellence Award

Senior Researcher in Aitkhozhin Institute of Molecular Biology and Biochemistry, Kazakhstan

Dr. Dauren Botbayev earned a Bachelor of Technics and Technologies in Biotechnology and a Master of Natural Sciences from Al-Farabi Kazakh National University, where he also pursued his Ph.D. in Biotechnology. He completed advanced English training at the Intensive English Institute, University of California San Diego, and obtained a Master of Translational Biotechnology from the University of Southern California – Keck School of Medicine. He began his career at M.A. Aitkhozhin’s Institute of Molecular Biology and Biochemistry as a Lab Assistant and progressed to Research Scientist and Senior Researcher. He also served as a Research Assistant at the University of Bologna in Italy. In academia, he joined Satbayev University’s School of Chemical and Biological Engineering as a Lecturer and later advanced to Senior Lecturer. His academic and research career reflects strong expertise in biotechnology, molecular biology, and translational research.

Citation Metrics (Scopus)

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Citations
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h-index
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Featured Publications

 

Miguel Angel Alcantara-Ortigoza | Human Molecular Genetics | Best Researcher Award

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Dr. Miguel Angel Alcantara-Ortigoza | Human Molecular Genetics | Best Researcher Award

Academic Researcher in National Institute of Pediatrics, Mexico

Dr. Miguel Angel Alcantara-Ortigoza is a medical scientist with doctoral training in Molecular Biology, specializing in monogenic diseases and congenital malformations. His work at INP contributed to advancing the molecular understanding of inherited disorders, and he currently serves as Director of the Molecular Diagnosis Area at the DNA-GEN SC laboratory, where he has nearly 20 years of experience implementing and supervising molecular diagnostic testing for approximately 15,000 patients across Mexico and Latin America. He collaborates with rehabilitation centers, hospitals, private laboratories, and pharmaceutical companies such as Sanofi-Genzyme and Roche in areas including newborn screening and orphan drug development. With 72 publications, more than 554 citations across 523 documents, and an h-index of 14, he has established a strong scientific footprint in human genetics. His collaborations particularly with Prof. Marcela Vela Amieva’s group have led to pivotal contributions describing the genotypic spectrum underlying inborn metabolic diseases in Mexico. His research group reported the first molecular prenatal diagnosis for a monogenic disease in Mexico and recently proposed a rational diagnostic approach for families affected by orofacial clefts to enhance genetic counseling. His work continues to impact clinical genetics, molecular diagnostics, and the genomic characterization of congenital and metabolic disorders.

Profiles: Scopus | Orcid | Google Scholar | Staff Page

Featured Publications

Alcántara-Ortigoza, M. A., Vela-Amieva, M., González-del Angel, A., Reyna-Fabián, M. E., Fernández-Hernández, L., Estandía-Ortega, B., Guillén-López, S., López-Mejía, L., Ibarra-González, I., & Ruiz-Reyes, M. de la L. (2025). Biparental and androgenetic somatic mosaicism with presentation of non-syndromic severe neonatal hyperinsulinemia. International Journal of Molecular Sciences, 26(16), 7985.

Fernández-Lainez, C., Vela-Amieva, M., Reyna-Fabián, M., Fernández-Hernández, L., Guillén-López, S., López-Mejía, L., Alcántara-Ortigoza, M. Á., González-del Angel, A., Carrillo-Nieto, R. I., & Ortega-Valdez, E. (2024). Isolated methylmalonic acidemia in Mexico: Genotypic spectrum, report of two novel MMUT variants and a possible synergistic heterozygosity effect. Molecular Genetics and Metabolism Reports, 41, 101155.

Vela-Amieva, M., Alcántara-Ortigoza, M. A., González-del Angel, A., Fernández-Hernández, L., Reyna-Fabián, M. E., Estandía-Ortega, B., Guillén-López, S., López-Mejía, L., Belmont-Martínez, L., & Carrillo-Nieto, R. I. (2024). Concordance between biochemical and molecular diagnosis obtained by WES in Mexican patients with inborn errors of intermediary metabolism: Utility for therapeutic management. International Journal of Molecular Sciences, 25(21), 11722.

Alcántara-Ortigoza, M. A., Rodríguez-Lozano, A. L., Estandía-Ortega, B., González-del Angel, A., Díaz-García, L., Rivas-Larrauri, F. E., & Nájera-Velázquez, R. G. (2024). Does the esv3587290 copy number variation in the VANGL1 gene differ as a genetic factor for developing nephritis in Mexican childhood-onset systemic lupus erythematosus patients? Children, 11(6), 712.

Vela-Amieva, M., Alcántara-Ortigoza, M. A., González-del Angel, A., Ibarra-González, I., Fernández-Hernández, L., Guillén-López, S., López-Mejía, L., & Fernández-Lainez, C. (2023). In silico structural protein evaluation of the phenylalanine hydroxylase p.(Tyr77His) variant associated with benign hyperphenylalaninemia as identified through Mexican newborn screening. Children, 10(12), 1865.

González-del Angel, A., Ruiz-Herrera, A., Hernández-Martínez, N. L., Todd-Quiñones, C. G., Durán-McKinster, C., Herrera-Mora, P., & Alcántara-Ortigoza, M. A. (2023). Uncommon large and bilateral fibrous cephalic plaques in a patient with TSC2-related tuberous sclerosis complex. Children, 10(10), 1614.

González-del Angel, A., Alcántara-Ortigoza, M. A., Ramos, S., Algara-Ramírez, C., Hernández-Hernández, M. A., & Saenger-Rivas, L. (2023). Unusual trisomy X phenotype associated with a concurrent heterozygous 16p11.2 deletion: Importance of an integral approach for proper diagnosis. International Journal of Molecular Sciences, 24(19), 14643.

Ashton, C. J., Perveen, R., Beaman, G., Crisponi, G., González-del Angel, A., Garza-Mayén, G., Alcántara-Ortigoza, M. A., O’Sullivan, J., & Clayton-Smith, J. (2022). 3MC syndrome: Molecular findings in previously reported and milder patients expand the natural history and phenotypic spectrum. Clinical Dysmorphology, 31(4), 157–165.

Huiqing Jiang | Nucleic Acid | Outstanding Contribution Award

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Prof. Huiqing Jiang | Nucleic Acid | Outstanding Contribution Award

Prof. Huiqing Jiang | Hebei Medical University | China

Prof. Huiqing Jiang is a distinguished Professor, Chief Physician, and Doctoral Supervisor at The Second Hospital of Hebei Medical University, where he also serves as Director of the Hebei Institute of Digestive Diseases and the Hebei Key Laboratory of Digestive Diseases. A recipient of the prestigious Special Government Allowance from the State Council of China, he has made outstanding contributions to the diagnosis and treatment of digestive system diseases. His clinical expertise encompasses endoscopic diagnosis and therapeutic interventions for gastrointestinal disorders, including endoscopic resection of early cancers and polyps, stricture dilation, stent placement, treatment of esophageal varices in cirrhosis, and biliary stone extraction with pancreatic stent insertion. As a pioneer in Hebei Province, he has introduced and advanced multiple endoscopic techniques that have transformed clinical practice and improved patient outcomes. His research primarily focuses on chronic liver diseases, particularly liver fibrosis, and gastrointestinal tumors, where he has established himself as a leading authority in digestive disease research. Prof. Jiang has served as the principal investigator for two National Natural Science Foundation of China projects and has successfully completed six provincial-level projects, earning significant recognition for his innovative contributions. His work has been honored with several prestigious awards, including the First-Class Prize of the Provincial Scientific and Technological Progress Award, three Third-Class Prizes, and the Young Teachers Award from the Huo Yingdong Education Foundation. He has published an impressive 160 peer-reviewed papers, including 11 SCI-indexed articles, with his highest impact publication appearing in the Journal of Hepatology (Impact Factor 9.334). His academic influence is reflected in his citation record of 1,866 citations across 1,714 documents and an h-index of 24, showcasing his sustained scholarly impact in the field. Additionally, he has edited or co-authored 16 authoritative medical textbooks such as Internal Medicine, Diagnostics, and Clinical Hepatology, contributing extensively to medical education and training. Prof. Jiang also holds significant editorial responsibilities, serving as Associate Editor-in-Chief of Gastroenterology and Hepatology and as a board member of several core medical journals. His leadership extends to professional associations as Standing Committee Member of the Chinese Society of Digestive Endoscopy and the Endoscopist Branch of the Chinese Medical Doctor Association, and as Chairman of both the Hebei Branch of the Digestive Endoscopist Association and the Hebei Society of Gastroenterology.

Profile:  Scopus

Featured Publications

piR-19521 facilitates cancer stem cell-like properties by enhancing ALX4 transcription via an enhancer RNA-like mechanism in colorectal cancer. International Journal of Biological Macromolecules.

Correction to: The role of the apoptosis-related protein BCL-B in the regulation of mitophagy in hepatic stellate cells during the regression of liver fibrosis. Experimental & Molecular Medicine, 51(1), 1–13.

Identification and validation of a novel predictive signature based on hepatocyte-specific genes in hepatocellular carcinoma by integrated analysis of single-cell and bulk RNA sequencing. BMC Medical Genomics.

Development and validation of risk prediction model for bacterial infections in acute liver failure patients. European Journal of Gastroenterology & Hepatology.

Effect of oxaliplatin on the activation of hepatic stellate cells and its mechanism. Journal of Clinical Hepatology.

Development and validation of a new prognostic model for patients with acute-on-chronic liver failure in intensive care unit. World Journal of Gastroenterology.

Identification of oxidative stress-related biomarkers associated with the development of acute-on-chronic liver failure using bioinformatics. Scientific Reports.

Evaluation of ITGB1 expression as a predictor of the therapeutic effects of immune checkpoint inhibitors in gastric cancer. BMC Gastroenterology.