Laila Jaragh-Alhadad | Medicinal Chemistry | Best Researcher Award

Assist. Prof. Dr. Laila Jaragh-Alhadad | Medicinal Chemistry | Best Researcher Award

Kuwait University, Kuwait

Author Profile

Scopus

Early Academic Pursuits

Assistant Professor Dr. Laila Jaragh-Alhadad began her academic journey in the field of Chemistry, earning her Bachelor’s degree in 2004 and Master’s degree in 2009 from Kuwait University, specializing in Petroleum Chemistry. Her exceptional academic performance and dedication to research earned her a prestigious Ph.D. scholarship from Kuwait University in 2011. She pursued her doctoral studies at Cleveland State University, USA, where she specialized in Clinical Bio-analytical Chemistry and successfully completed her Ph.D. in 2017. Her Ph.D. thesis, titled “Cholesterol conjugated heat shock protein 27 inhibitor as a novel anti-ovarian cancer agent,” reflected her early interest in drug design and medicinal chemistry, focusing on cancer therapeutics.

Professional Endeavors

Dr. Laila Jaragh-Alhadad’s professional career is rooted in excellence and service to science and society. She has been serving as an Assistant Professor in the Department of Chemistry at Kuwait University since 2017. Prior to this, she gained valuable experience as a Chemist at Kuwait’s Environmental Public Authority (2009–2011) and as a Graduate Scientific Assistant at Kuwait University (2006–2008). Her professional endeavors extend to administrative and academic committees, where she has contributed to curriculum design, laboratory safety, student affairs, and applied chemistry coordination. Dr. Alhadad also undertook a sabbatical at the Lerner Research Institute, Cleveland Clinic, USA (2021–2022), further enhancing her expertise in biomedical research and medicinal chemistry applications.

Contributions and Research Focus

Dr. Alhadad’s research focus lies at the intersection of medicinal chemistry, bioanalytical chemistry, and cancer pharmacology. Her pioneering studies involve the synthesis and encapsulation of novel anticancer agents targeting proteins such as HSP27, HER2, and tubulin. She has led several funded research projects at Kuwait University, including investigations into low-density lipoprotein (LDL)-encapsulated anticancer drugs, triazole derivatives, and SIRT2 inhibitors. Her work on targeted drug delivery systems has opened new possibilities for more effective cancer treatments with reduced toxicity. Through her innovative use of in-silico and in-vitro models, Dr. Alhadad has made significant contributions to the advancement of modern medicinal chemistry and drug discovery.

Impact and Influence

The impact and influence of Dr. Laila Jaragh-Alhadad are evident across academic, research, and community platforms. She has actively participated in international conferences in Kuwait, the UK, the USA, Italy, Greece, and China, presenting her cutting-edge research on cancer-targeted therapies. Her commitment to science education and public engagement includes serving on various committees, writing awareness articles on cancer research, and volunteering in scientific and social initiatives. Recognized globally, she has received multiple prestigious awards, including the Best Research Award at the 595th International Conference on Recent Advances in Medical and Health Sciences (Oxford, 2019), and the International Research Award on Oncology and Cancer Research (USA, 2021). Her distinguished teaching award (2020–2021) reflects her excellence in both research and education.

Academic Citations

Dr. Alhadad’s research publications have been highly cited in international journals, demonstrating the broad relevance of her work in medicinal chemistry and cancer therapeutics. Her studies on HSP27 inhibitors and LDL-based drug delivery systems are frequently referenced by other researchers in bio-analytical chemistry and pharmaceutical sciences. The consistent academic citations her work receives underscore her contributions to global scientific knowledge and highlight her position as a respected scholar in the field.

Legacy and Future Contributions

Looking toward the future, Assistant Professor Dr. Laila Jaragh-Alhadad is committed to expanding her research in medicinal chemistry, particularly in the development of targeted therapies for women’s cancers. Her ongoing projects focus on hybrid in-silico/in-vitro drug design and the encapsulation of bioactive compounds for enhanced therapeutic delivery. Through her mentorship, academic leadership, and groundbreaking research, she continues to inspire young scientists and contribute to Kuwait University’s growing reputation for excellence in scientific innovation. Her enduring legacy will be defined by her dedication to advancing medicinal chemistry, improving cancer treatments, and promoting interdisciplinary collaboration across chemistry and biomedical sciences.

Medicinal Chemistry

Assistant Professor Dr. Laila Jaragh-Alhadad’s exceptional research in medicinal chemistry has led to significant advancements in targeted drug delivery and cancer therapeutics. Her pioneering studies on bioactive molecule design, protein inhibition, and encapsulation technologies are transforming the future of medicinal chemistry. Through her leadership, innovation, and global scientific recognition, she continues to shape the evolution of medicinal chemistry toward more effective and personalized cancer treatments.

Featured Publications

Design, synthesis, and antiproliferative activity of antipyrine linked 2-amino-quinoline-3-carbonitrile derivatives as potential dual EGFR/HER-2 inhibitors

Journal: Journal of Molecular Structure

Year: 2026

Citations: 0


A novel one-pot microwave assisted green synthesis of pyridinyl-1,3,5-triazine-2,4-diamine hybrids as potent antimicrobial agents

Journal: BMC Chemistry

Year: 2025

Zsuzsanna Suba | Cancer research | Breakthrough Research Award

Prof. Dr. Zsuzsanna Suba | Cancer research | Breakthrough Research Award

National Institute of Oncology, Budapest, Hungary

Profile

Orcid

🎓 Early Academic Pursuits

Prof. Dr. Zsuzsanna Suba embarked on her academic journey at the Semmelweis University of Medicine, earning her Doctor of Medicine in 1971. Her early interest in both general and oral pathology led her to pursue multiple certifications: Board certification in Pathology (1975), Dentistry and Stomatology (1986), and Oral Pathology (Sheffield, UK, 1987). She further advanced her academic credentials by completing a Ph.D. in 1994 and attaining the Habilitated Medical Science (Habil.Med.Sci.) degree in 2004, marking her as a leading expert in her field.

🩺 Professional Endeavors

Prof. Suba's career commenced in 1971 as an Assistant Professor at the 1st Institute of Pathology and Experimental Cancer Research at her alma mater. She then led the Oral Pathology Division within the Department of Oral and Maxillofacial Surgery at Semmelweis University from 1982 to 2011. In 2004, she was officially named Professor of Oral Pathology. Her final academic post was at the National Institute of Oncology, where she served as Professor of Pathology from 2011 until becoming Professor Emeritus in 2017, reflecting her decades-long contribution to academic medicine.

🧬 Contributions and Research Focus

Prof. Suba’s research has significantly shaped understanding in several niche yet vital domains of pathology. Her early work investigated cell proliferation kinetics and virus-induced experimental tumors. She later pioneered studies into the pathology of bone replacement in the oral and maxillofacial region, and the clinical and pathological evaluation of chemotherapy outcomes in oral cancers. Notably, she explored the correlations between metabolic disorders (like type-2 diabetes, insulin resistance, and obesity) and cancer incidence, particularly oral and breast cancers. Her groundbreaking research highlighted the hormonal mechanisms involved in tumor progression, the role of estrogen signaling in cancer risk, and even proposed a genome-stabilizing therapeutic model for breast cancer cases.

🌍 Impact and Influence

Prof. Suba’s research has had a substantial impact on the epidemiological and hormonal understanding of cancer biology, especially in women’s health. Her bold interpretations of the paradoxes in antiestrogen treatments in breast cancer, and her promotion of causal therapy over symptomatic treatment, have sparked meaningful discourse in oncological and hormonal therapy communities. Her findings bridge molecular biology, pathology, endocrinology, and clinical practice, positioning her as a multidisciplinary influencer in medical science.

📈 Academic Citations and Publications

With 128 peer-reviewed articles accumulating a total impact factor of 122.647, Prof. Suba has maintained a strong presence in the scientific literature. She has authored 12 books, 42 book chapters—many in English—and accumulated 1,230 independent citations as a first or last author. These achievements speak volumes about the relevance and longevity of her scientific contributions.

🖥️ Technical and Research Skills

Her academic career has been deeply rooted in molecular and surgical pathology techniques, including histopathological diagnostics, tumor cell kinetic analysis, and clinical trials of chemotherapy and hormone therapy outcomes. Her interdisciplinary acumen allows her to integrate pathology, biochemistry, endocrinology, and epidemiology in both laboratory and clinical research contexts.

👩‍🏫 Teaching Experience and Recognition

A beloved educator, Prof. Suba has been honored multiple times for her teaching excellence. She received the Teacher’s Award from Semmelweis University (1998) and again in 2008, this time chosen directly by students. She is known for her dedicated mentorship, ability to simplify complex medical content, and commitment to fostering critical thinking in future clinicians and researchers.

🏅 Honors and Awards

Throughout her illustrious career, she has been decorated with prestigious awards such as the MOTESZ Award for Young Researchers (1976), the Markusovszky Award (1993), and the recent Distinguished Cancer Treatment Innovation Award (2024) from Scifax. These accolades recognize both her innovative research and her lifelong dedication to cancer pathology.

🌟 Legacy and Future Contributions

Now serving as Professor Emeritus, Prof. Suba remains a venerated figure in oncology and pathology. Her visionary work on hormonal and metabolic links to cancer continues to guide current investigations. Her legacy lies not only in her scientific outputs but also in the inspired careers of countless students and clinicians she mentored. Her genome-stabilization framework offers a promising direction for personalized cancer therapy, and future researchers will undoubtedly build upon her foundational insights for decades to come.

Selected Publications

  • Suba Zsuzsanna (2024)
    DNA Damage Responses in Tumors Are Not Proliferative Stimuli, but Rather They Are DNA Repair Actions Requiring Supportive Medical Care
    Cancers (Basel), 16(8):1573. April 19, 2024.

  • Suba Zsuzsanna (2024)
    Estrogen Regulated Genes Compel Apoptosis in Breast Cancer Cells, Whilst Stimulate Antitumor Activity in Peritumoral Immune Cells in a Janus‑Faced Manner
    Current Oncology, 31(9):4885–4907. August 24, 2024.

  • Suba Zsuzsanna (2023)
    Rosetta Stone for Cancer Cure: Comparison of the Anticancer Capacity of Endogenous Estrogens, Synthetic Estrogens and Antiestrogens
    Oncology Reviews, 17:10708 (eCollection). April 19, 2023.

  • Suba Zsuzsanna (2020)
    Compensatory Estrogen Signal Is Capable of DNA Repair in Antiestrogen‑Responsive Cancer Cells via Activating Mutations
    Journal of Oncology & Therapy (or equivalent publication). 2020.

  • Suba Zsuzsanna (2018)
    Amplified Crosstalk Between Estrogen Binding and GFR Signaling Mediated Pathways of ER Activation Drives Responses in Tumors Treated with Endocrine Disruptors
    Recent Patents on Anticancer Drug Discovery, 13(4):428–444. 2018.