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Prof. John T McDevitt | Dentistry | Best Researcher Award

ย Professor of New York University, United States

๐ŸŒŸ Professor John T. McDevitt is a distinguished figure in biomaterials and ‘smart diagnostic‘ technologies at NYU College of Dentistry. As a visionary leader and founder of multiple diagnostic firms like OraLiva, he pioneers innovations for early disease detection. His extensive research, comprising 219+ publications and 145+ patents, reflects his profound impact on healthcare. Recognized with accolades such as the AACC Wallace H. Coulter Lectureship Award and the Presidential Young Investigator Award, Dr. McDevitt’s work integrates AI-linked sensors for diseases like oral cancer and COVID-19, securing over $47M in NIH funding. His contributions epitomize excellence in translating bioscience into transformative clinical solutions. ๐Ÿฅ

Professional Profile:

Education๐ŸŽ“

๐ŸŽ“ Professor John T. McDevitt pursued his academic journey with zeal, earning a B.S. in Chemistry/Sensors Devices from California Polytechnic State University in 1982. He continued his quest for knowledge at Stanford University, where he obtained his Ph.D. in Physical/Materials Chemistry in 1987. Following this, he conducted postdoctoral research in Analytical/Materials Chemistry at the University of North Carolina from 1987 to 1989. These formative years laid the foundation for his illustrious career in biomaterials and bioengineering, shaping his expertise in developing groundbreaking ‘smart diagnostic‘ technologies that advance healthcare. ๐Ÿ“š

Professional Experience ๐Ÿ“š

๐ŸŒŸ Professor John T. McDevitt brings over three decades of distinguished professional experience to his role. Currently serving as a Full Professor in the Division of Biomaterials at New York University College of Dentistry, he is also affiliated with the Bioengineering Institute and the Department of Chemical and Biomolecular Engineering at the Tandon School of Engineering. Previously, he held notable positions such as Chair of the Department of Biomaterials at NYU and the Brown-Weiss Professor of Bioengineering and Chemistry at Rice University. His leadership extends to directing multiple research consortia and clinical studies, driving innovations in smart diagnostic technologies for early disease detection and management. ๐Ÿ†

Research Interest ๐Ÿ”

๐Ÿ”ฌ Professor John T. McDevitt is deeply engaged in pioneering research at the intersection of biomaterials, bioengineering, and chemical engineering. His research endeavors focus on developing advanced ‘smart diagnostic‘ technologies aimed at revolutionizing healthcare delivery. His primary interests lie in creating miniaturized sensor ensembles and lab-on-a-chip systems for rapid, accurate disease diagnosis at the point of care. With a strong emphasis on integrating artificial intelligence with biomedical devices, his work spans critical areas such as oral cancer detection, COVID-19 severity assessment, and cardiac disease monitoring. Professor McDevitt’s innovative approach aims to enhance early detection capabilities, thereby improving patient outcomes and healthcare efficiency. ๐ŸŒ

Award and Honor๐Ÿ†

๐Ÿ† Professor John T. McDevitt has garnered prestigious awards and honors for his pioneering contributions to biomedical engineering and diagnostics. His groundbreaking work in developing ‘smart diagnostic‘ technologies has earned him recognition, including the 2016 AACC Wallace H. Coulter Lectureship Award and the Popular Science Best of What’s New Award in the Medical Device Category. He has also been honored with the Presidential Young Investigator Award and the Grace Fellowship, Stanford University. These accolades underscore his leadership in translating cutting-edge research into impactful clinical applications, further solidifying his reputation as a trailblazer in the field of bio-nanotechnology. ๐ŸŒŸ

Research Skills๐ŸŒŸ

๐Ÿ”ฌ Professor John T. McDevitt is renowned for his exceptional research skills in bio-nanotechnology and biomedical engineering. His expertise lies in developing advanced diagnostic technologies, including ‘smart diagnostic‘ devices and lab-on-a-chip systems. With over 219 peer-reviewed publications and more than 145 patents/patent applications to his name, he has made significant contributions to the field. Prof. McDevitt’s research focuses on integrating nanotechnology with clinical diagnostics, leveraging AI and mini-sensor ensembles for point-of-care testing. His innovative approach has revolutionized disease detection and monitoring, addressing critical healthcare challenges through interdisciplinary collaboration and cutting-edge scientific inquiry. ๐ŸŒ

Achievements๐Ÿ†

  • ๐Ÿ”ฌ Developed pioneering ‘smart diagnostic’ technologies.๐Ÿ† Received the 2016 AACC Wallace H. Coulter Lectureship Award.

    ๐ŸŒŸ Honored with the Kathleen C. Kinnally Outstanding Scientific Achievement Award.

    ๐ŸŽ–๏ธ Recognized by Popular Science with the Best of What’s New Award in Medical Devices.

    ๐Ÿ… Received the Presidential Young Investigator Award.

    ๐Ÿ“ˆ Elevated the field with over 219 peer-reviewed publications and 145 patents.

    ๐Ÿ’ก Founded multiple diagnostic companies, including OraLiva, advancing clinical diagnostics.

    ๐Ÿ’ฐ Raised over $47M in federal and foundation funding for research.

    ๐ŸŒ Contributed to global health initiatives like HIV monitoring in Africa.

    ๐ŸŽ“ Distinguished career spanning leadership roles at Rice University and NYU, shaping the future of bioengineering and biomaterials.

Projects๐Ÿ’ง๐Ÿ”ฌ

  • ๐Ÿ”ฌ Point-of-Care Oncology Tool: Developed the first point-of-care oncology tool for precision medicine to monitor malignant transitions and recurrence in patients with oral epithelial dysplasia and prior oral cavity cancers.๐Ÿงช Lab-on-a-Chip System for Saliva-Based Diagnostics: Created a groundbreaking lab-on-a-chip system for saliva-based diagnostics aimed at cardiac disease, integrating 17 protein biomarkers for effective diagnosis.

    ๐Ÿฆท Monitoring Oral Cancer Patients: Led a project using novel lab-on-a-chip ensembles to monitor oral cancer patients, identifying cellular markers crucial for early detection and treatment.

    ๐Ÿ” Texas Cancer Diagnostics Pipeline Consortium: Spearheaded multiple initiatives under this consortium focusing on oral, ovarian, and prostate cancers, employing advanced bio-nanochips to enhance diagnostic accuracy.

    ๐Ÿš” Saliva-Based Drug Test at Point of Arrest: Designed bio-nanochips for saliva-based drug tests used at the point of arrest, aiding in the detection of drugs and metabolites efficiently.

Publications ๐Ÿ“š

๐Ÿ“š Current developments in salivary diagnostics

  • Authors: CS Miller, JD Foley, AL Bailey, CL Campell, RL Humphries, …
  • Journal: Biomarkers in Medicine
  • Volume: 4
  • Issue: 1
  • Pages: 171-189
  • Citations: 509
  • Year: 2010

๐Ÿ”ฌ Aptamer-based sensor arrays for the detection and quantitation of proteins

  • Authors: R Kirby, EJ Cho, B Gehrke, T Bayer, YS Park, DP Neikirk, JT McDevitt, …
  • Journal: Analytical Chemistry
  • Volume: 76
  • Issue: 14
  • Pages: 4066-4075
  • Citations: 402
  • Year: 2004

๐Ÿ” Application of microchip assay system for the measurement of C-reactive protein in human saliva

  • Authors: N Christodoulides, S Mohanty, CS Miller, MC Langub, PN Floriano, …
  • Journal: Lab on a Chip
  • Volume: 5
  • Issue: 3
  • Pages: 261-269
  • Citations: 316
  • Year: 2005

๐Ÿ‘… Solution-based analysis of multiple analytes by a sensor array: toward the development of an โ€œelectronic tongueโ€

  • Authors: JJ Lavigne, S Savoy, MB Clevenger, JE Ritchie, B McDoniel, SJ Yoo, …
  • Journal: Journal of the American Chemical Society
  • Volume: 120
  • Issue: 25
  • Pages: 6429-6430
  • Citations: 295
  • Year: 1998

๐Ÿ”ฌ Detection system based on an analyte reactive particle

  • Authors: JT McDevitt, EV Anslyn, JB Shear, DP Neikirk
  • Publication: US Patent 6,602,702
  • Citations: 289
  • Year: 2003

๐ŸŒŸ Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels

  • Authors: JV Jokerst, A Raamanathan, N Christodoulides, PN Floriano, AA Pollard, …
  • Journal: Biosensors and Bioelectronics
  • Volume: 24
  • Issue: 12
  • Pages: 3622-3629
  • Citations: 283
  • Year: 2009

๐Ÿฉบ A microchip CD4 counting method for HIV monitoring in resource-poor settings

  • Authors: WR Rodriguez, N Christodoulides, PN Floriano, S Graham, S Mohanty, …
  • Journal: PLoS Medicine
  • Volume: 2
  • Issue: 7
  • Pages: e182
  • Citations: 272
  • Year: 2005

๐Ÿ”ฌ Development of multianalyte sensor arrays composed of chemically derivatized polymeric microspheres localized in micromachined cavities

  • Authors: A Goodey, JJ Lavigne, SM Savoy, MD Rodriguez, T Curey, A Tsao, …
  • Journal: Journal of the American Chemical Society
  • Volume: 123
  • Issue: 11
  • Pages: 2559-2570
  • Citations: 260
  • Year: 2001

๐Ÿ’ก Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study

  • Authors: PN Floriano, N Christodoulides, CS Miller, JL Ebersole, J Spertus, …
  • Journal: Clinical Chemistry
  • Volume: 55
  • Issue: 8
  • Pages: 1530-1538
  • Citations: 256
  • Year: 2009

๐Ÿงฌ Differential receptors create patterns diagnostic for ATP and GTP

  • Authors: SC McCleskey, MJ Griffin, SE Schneider, JT McDevitt, EV Anslyn
  • Journal: Journal of the American Chemical Society
  • Volume: 125
  • Issue: 5
  • Pages: 1114-1115
  • Citations: 245
  • Year: 2003

๐Ÿ”ฌ A microchip-based multianalyte assay system for the assessment of cardiac risk

  • Authors: N Christodoulides, M Tran, PN Floriano, M Rodriguez, A Goodey, M Ali, …
  • Journal: Analytical Chemistry
  • Volume: 74
  • Issue: 13
  • Pages: 3030-3036
  • Citations: 229
  • Year: 2002

๐ŸŽจ Self-assembly of conjugated polymers at the air/water interface. Structure and properties of Langmuir and Langmuirโˆ’ Blodgett films of amphiphilic regioregular polythiophenes

  • Authors: N Reitzel, DR Greve, K Kjaer, PB Howes, M Jayaraman, S Savoy, …
  • Journal: Journal of the American Chemical Society
  • Volume: 122
  • Issue: 24
  • Pages: 5788-5800
  • Citations: 223
  • Year: 2000

๐Ÿ› ๏ธ Method and apparatus for the delivery of samples to a chemical sensor array

  • Authors: JT McDevitt, EV Anslyn, JB Shear, DP Neikirk
  • Publication: US Patent 6,713,298
  • Citations: 212
  • Year: 2004

๐Ÿ”ง Systems and methods including self-contained cartridges with detection systems and fluid delivery systems

  • Authors: JT McDevitt, K Ballard, NJ Christodoulides, PN Floriano, GW Simmons
  • Publication: US Patent App. 11/993,705
  • Citations: 203
  • Year: 2010

๐Ÿงช Boronic acid based peptidic receptors for pattern-based saccharide sensing in neutral aqueous media, an application in real-life samples

  • Authors: NY Edwards, TW Sager, JT McDevitt, EV Anslyn
  • Journal: Journal of the American Chemical Society
  • Volume: 129
  • Issue: 44
  • Pages: 13575-13583
  • Citations: 203
  • Year: 2007
John T McDevitt | Dentistry | Best Researcher Award

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