Dr. Hua He | Cardiovascular diseases | Best Researcher Award

Beijing Anzhen Hospital Affiliated to Capital Medical University, China

Profile

🎓 Early Academic Pursuits

Professor Hua He graduated from the prestigious Peking Union Medical College in 2006, earning a doctorate in internal medicine. This solid academic foundation laid the groundwork for his career in cardiovascular medicine and clinical research, with an early focus on coronary heart disease, arrhythmia, and heart failure.

💼 Professional Endeavors

Currently serving as a Professor and Chief Physician at Beijing Anzhen Hospital, Capital Medical University, Professor He has dedicated himself to advancing clinical and basic research in cardiovascular diseases. His leadership includes managing several key projects related to ischemic heart disease and stem cell therapies, reflecting his commitment to bridging clinical practice and innovative research.

🔬 Contributions and Research Focus

Over recent years, Professor He has focused on the therapeutic potential of human umbilical cord mesenchymal stem cell exosomes in the treatment of ischemic heart disease. His pioneering work demonstrates how these exosomes improve ventricular remodeling and long-term cardiac function following myocardial infarction. He has also contributed to elucidating the molecular mechanisms and biological dynamics of stem cell-derived exosomes both in vivo and in vitro, publishing 17 articles in high-impact journals.

🌍 Impact and Influence

Through his role as senior editor of Clinical and Applied Thrombosis Hemostasis and reviewer for Stem Cell Research and Therapy, Professor He has influenced the direction of research in cardiovascular regenerative medicine. His expertise is further recognized by his involvement as a project reviewer for the National Natural Science Foundation of China and as a medical identification expert for several Beijing medical associations.

📊 Academic Citations

With 17 journal publications and a citation index of 7, Professor He’s research contributions are well acknowledged in the scientific community. His ongoing research projects (eight completed or in progress) and patent filings highlight a strong commitment to innovation and knowledge dissemination.

💻 Technical Skills

Professor He possesses advanced technical skills in stem cell biology, molecular analysis, and cardiovascular disease modeling. His proficiency in translational research techniques has enabled successful exploration of novel therapies for myocardial ischemia/reperfusion injury.

🎓 Teaching Experience

In addition to his research activities, Professor He contributes to medical education by mentoring young clinicians and researchers, fostering the next generation of cardiovascular specialists through practical and theoretical training.

🔮 Legacy and Future Contributions

Professor He’s research advances the frontier of regenerative cardiovascular medicine, particularly in stem cell-derived exosome therapy. His ongoing projects and expert collaborations promise significant breakthroughs that could transform treatment protocols for ischemic heart disease worldwide.

📚 Selected Publications

He, H., et al. "Human umbilical cord mesenchymal stem cell exosomes improve ventricular remodeling after myocardial infarction." Journal of Cardiovascular Research, 2021.
He, H., Wang, X., et al. "Therapeutic effects of mesenchymal stem cell exosomes on ischemia/reperfusion injury in rat models." Stem Cell Therapy, 2022.
He, H., Zhang, Y., et al. "Molecular mechanisms of exosome-mediated cardiac repair post-infarction." Cellular and Molecular Medicine, 2020.
He, H., Li, Q., et al. "In vivo biodistribution and pharmacodynamics of human umbilical cord MSC-derived exosomes." Frontiers in Cardiovascular Medicine, 2019.
He, H., Chen, J., et al. "Mesenchymal stem cell exosomes modulate inflammation and fibrosis in cardiac tissue." International Journal of Cardiology, 2021.
He, H., Liu, S., et al. "Safety assessment of MSC exosome therapy in myocardial ischemia/reperfusion." Stem Cells Translational Medicine, 2023.
He, H., et al. "Exosome-based delivery of therapeutic molecules for heart failure treatment." Theranostics, 2022.

Dr. Viviane Zotzmann | Intensive Care Medicine | Best Researcher Award

Ortenau Klinikum Offenburg-Kehl, Germany.

PD Dr. med. Viviane Zotzmann is a Senior Consultant for Intensive Care Medicine at Ortenau Klinikum, specializing in internal medicine and cardiology with additional expertise in emergency and intensive care medicine. She has trained in both municipal hospitals and the University Hospital of Freiburg. Dr. Zotzmann is currently responsible for two intensive care units in Offenburg and Lahr. Her research focuses on ECMO therapy, with particular interest in survival predictors, quality of life, and functional outcomes post-therapy. She is an active member of professional societies such as DGK, DEGUM, DIVI, and DGIM.

Profile

Orcid

🎓 Education

Dr. Viviane Zotzmann holds a Doctor of Medicine (Dr. med.) degree from the University of Tübingen (2005). She is a board-certified specialist in Internal Medicine (2013), Cardiology (2017), and Intensive Care Medicine (2018), with further certification in Cardiovascular Intensive and Emergency Medicine (2022). In addition, she is an Advanced Life Support & Pediatric Life Support Provider (2023). Dr. Zotzmann has also completed additional training in Sonography, Emergency Medicine, and Radiation Protection.

🏥 Professional Experience

Dr. Viviane Zotzmann is a highly experienced medical professional specializing in intensive care, cardiology, and emergency medicine. She currently serves as the Head of Intensive Care Medicine at Ortenau Klinikum (2025 – Present). Previously, she held the position of Senior Consultant at Ortenau Klinikum (2023 – 2025), overseeing Cardiology, Pneumology, Angiology, Geriatrics, Intensive Care, and Thoracic Surgery.

From 2020 to 2023, Dr. Zotzmann was the Lead Physician of Medical Intensive Care Units at University Hospital Freiburg, following her role as a Specialist Physician at the same institution (2016 – 2020). Before that, she served as Senior Physician in Internal Medicine/Cardiology at Zollernalbklinikum (2014 – 2015).

Her medical journey began with specialist training in Internal Medicine & Cardiology at KKH Sigmaringen (2010 – 2014), solidifying her expertise in critical and cardiovascular care.

🔬 Research Interests

Extracorporeal Membrane Oxygenation (ECMO) therapy

Predictors of survival in VV-ECMO and VA-ECMO patients

Quality of life and mental health in post-ECMO patients

Pulmonary embolism diagnosis in ICU patients

Advanced intensive care monitoring and life-support techniques

🏆 Awards & Recognitions

Recognized contributor to ECMO research

Published in high-impact journals such as Intensive Care Medicine and Membranes (Basel)

Cited over 1,044 times with an h-index of 18

📚 Selected Publications

Quality of Life and Mental Health in COVID-ARDS Survivors After V-V ECMO Support: Results from the Freiburg ECMO Outcome Study (FEOS)
Journal of Clinical Medicine, 2025-03-24
DOI: 10.3390/jcm14072206
Contributors: Dawid L. Staudacher, Meret Felder, Markus Jäckel, Felix A. Rottmann, Alexander Supady, Xavier Bemtgen, Philipp Diehl, Tobias Wengenmayer, Viviane Zotzmann

Combining Lung Ultrasound and Wells Score for Diagnosing Pulmonary Embolism in Critically Ill COVID-19 Patients
Journal of Thrombosis and Thrombolysis, 2021-07-03
DOI: 10.1007/s11239-020-02323-0
Contributors: Viviane Zotzmann, Corinna N. Lang, Tobias Wengenmayer, Xavier Bemtgen, Bonaventura Schmid, Katharina Mueller-Peltzer, Alexander Supady, Christoph Bode, Daniel Duerschmied, Dawid L. Staudacher

Combining Lung Ultrasound and Wells Score for Diagnosing Pulmonary Embolism in Critically Ill COVID-19 Patients (Preprint)
2020-09-08
DOI: 10.21203/rs.3.rs-70085/v1
Contributors: Viviane Zotzmann, Corinna Nadine Lang, Tobias Wengenmayer, Xavier Bemtgen, Bonaventura Schmid, Katharina Mueller-Peltzer, Alexander Supady, Christoph Bode, Daniel Duerschmied, Dawid L. Staudacher

Venoarterial Extracorporeal Membrane Oxygenation Decannulation Using the Novel Manta Vascular Closure Device
European Heart Journal: Acute Cardiovascular Care, 2020-05-04
DOI: 10.1177/2048872620918707
Author: V. Zotzmann

Are Subpleural Consolidations Indicators for Segmental Pulmonary Embolism in COVID-19?
Intensive Care Medicine, 2020-04-23
DOI: 10.1007/s00134-020-06044-z
Author: V. Zotzmann

Hua He | Cardiovascular diseases | Best Researcher Award