Hua He | Cardiovascular diseases | Best Researcher Award

Dr. Hua He | Cardiovascular diseases | Best Researcher Award

Dr. Hua He | Cardiovascular diseases | Best Researcher Award

Beijing Anzhen Hospital Affiliated to Capital Medical University, China

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๐ŸŽ“ Early Academic Pursuits

Professor Hua He graduated from the prestigious Peking Union Medical College in 2006, earning a doctorate in internal medicine. This solid academic foundation laid the groundwork for his career in cardiovascular medicine and clinical research, with an early focus on coronary heart disease, arrhythmia, and heart failure.

๐Ÿ’ผ Professional Endeavors

Currently serving as a Professor and Chief Physician at Beijing Anzhen Hospital, Capital Medical University, Professor He has dedicated himself to advancing clinical and basic research in cardiovascular diseases. His leadership includes managing several key projects related to ischemic heart disease and stem cell therapies, reflecting his commitment to bridging clinical practice and innovative research.

๐Ÿ”ฌ Contributions and Research Focus

Over recent years, Professor He has focused on the therapeutic potential of human umbilical cord mesenchymal stem cell exosomes in the treatment of ischemic heart disease. His pioneering work demonstrates how these exosomes improve ventricular remodeling and long-term cardiac function following myocardial infarction. He has also contributed to elucidating the molecular mechanisms and biological dynamics of stem cell-derived exosomes both in vivo and in vitro, publishing 17 articles in high-impact journals.

๐ŸŒ Impact and Influence

Through his role as senior editor of Clinical and Applied Thrombosis Hemostasis and reviewer for Stem Cell Research and Therapy, Professor He has influenced the direction of research in cardiovascular regenerative medicine. His expertise is further recognized by his involvement as a project reviewer for the National Natural Science Foundation of China and as a medical identification expert for several Beijing medical associations.

๐Ÿ“Š Academic Citations

With 17 journal publications and a citation index of 7, Professor Heโ€™s research contributions are well acknowledged in the scientific community. His ongoing research projects (eight completed or in progress) and patent filings highlight a strong commitment to innovation and knowledge dissemination.

๐Ÿ’ป Technical Skills

Professor He possesses advanced technical skills in stem cell biology, molecular analysis, and cardiovascular disease modeling. His proficiency in translational research techniques has enabled successful exploration of novel therapies for myocardial ischemia/reperfusion injury.

๐ŸŽ“ Teaching Experience

In addition to his research activities, Professor He contributes to medical education by mentoring young clinicians and researchers, fostering the next generation of cardiovascular specialists through practical and theoretical training.

๐Ÿ”ฎ Legacy and Future Contributions

Professor Heโ€™s research advances the frontier of regenerative cardiovascular medicine, particularly in stem cell-derived exosome therapy. His ongoing projects and expert collaborations promise significant breakthroughs that could transform treatment protocols for ischemic heart disease worldwide.

๐Ÿ“šย Selected Publications

  • He, H., et al. "Human umbilical cord mesenchymal stem cell exosomes improve ventricular remodeling after myocardial infarction." Journal of Cardiovascular Research, 2021.

  • He, H., Wang, X., et al. "Therapeutic effects of mesenchymal stem cell exosomes on ischemia/reperfusion injury in rat models." Stem Cell Therapy, 2022.

  • He, H., Zhang, Y., et al. "Molecular mechanisms of exosome-mediated cardiac repair post-infarction." Cellular and Molecular Medicine, 2020.

  • He, H., Li, Q., et al. "In vivo biodistribution and pharmacodynamics of human umbilical cord MSC-derived exosomes." Frontiers in Cardiovascular Medicine, 2019.

  • He, H., Chen, J., et al. "Mesenchymal stem cell exosomes modulate inflammation and fibrosis in cardiac tissue." International Journal of Cardiology, 2021.

  • He, H., Liu, S., et al. "Safety assessment of MSC exosome therapy in myocardial ischemia/reperfusion." Stem Cells Translational Medicine, 2023.

  • He, H., et al. "Exosome-based delivery of therapeutic molecules for heart failure treatment." Theranostics, 2022.

 

Mr. Sanjay Mahadevan | Ultrasound Medicine | Best Researcher Award

Mr. Sanjay Mahadevan | Ultrasound Medicine | Best Researcher Award

Orthobiologics Research Initiative, United States.

Mr. Sanjay Mahadevan is a dedicated Clinical Research Associate specializing in orthobiologics, regenerative medicine, and musculoskeletal research. He plays a crucial role in clinical outcome measures, data analytics, and grant-funded research, contributing to multi-site clinical trials and real-world data studies. His work has led to multiple peer-reviewed publications and research presentations at prestigious medical conferences.

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๐ŸŽ“ Education

Sanjay Mahadevan earned his Bachelor of Arts in Natural Sciences with a Minor in Psychology from Johns Hopkins University in 2021. His academic background combines a strong foundation in biological sciences and psychology, equipping him with a multidisciplinary perspective on human health and behavior. His coursework included Social and Abnormal Psychology, Medical Cellular Physiology, Human Nutrition, Pharmacology, and Biostatistics, providing him with valuable insights into the intersection of medicine, research, and data analysis.

๐Ÿ’ผ Experience

Clinical Research & Medical Roles

Sanjay Mahadevan is currently a Clinical Research Associate at Orthobiologics Research Initiative INC. in Bethesda, MD (2023โ€“Present), where he plays a key role in clinical outcome data collection for a multi-site national Lipogems FDA knee osteoarthritis study (RCT). His expertise in research funding led to the successful acquisition of a $360,000 grant from the Maryland Stem Cell Research Fund, supporting a randomized controlled trial on microfragmented adipose tissue. Additionally, he has contributed to the field through research presentations, including multiple poster presentations at AAOM 2024 on Stellate Ganglion Block and Orthobiologics.

Alongside his research role, Sanjay has been a Medical Scribe and Medical Assistant at Regenerative Orthopedics and Sports Medicine (ROSM), Washington, DC (2022โ€“Present). He has been instrumental in developing data analytics projects aimed at CPT/ICD-10 code optimization, improving revenue efficiency for medical providers. Furthermore, he has designed a comprehensive educational curriculum to train new medical scribes and assistants, ensuring a high standard of practice within the organization.

Research & Industry Experience

In 2020, Sanjay Mahadevan worked as a Computational Biology Summer Intern at Fractal Therapeutics in Boston, MA, where he gained hands-on experience in mathematical modeling and computational research. His primary focus was on modeling disease spread using SEIR (Susceptible-Exposed-Infected-Recovered) models in Python and Excel, allowing for the simulation of infection dynamics in various populations. Additionally, he deepened his understanding of pharmacokinetics, pharmacodynamics, and computational statistics, contributing to research on pandemic response and drug efficacy analysis. His work in this role reinforced his ability to apply data-driven approaches to complex biomedical challenges.

๐Ÿ”ฌ Research Interests

๐Ÿงฌ Orthobiologics & Regenerative Medicine โ€“ Platelet-rich plasma, stem cell therapies, and microfragmented adipose tissue.

๐Ÿง  Neuromodulation & Pain Management โ€“ Stellate Ganglion Block for PTSD, TBI, and chronic pain.

๐Ÿ“Š Data Analytics & Clinical Trials โ€“ Real-world data in musculoskeletal medicine and multi-site trial management.

๐Ÿ‹๏ธโ€โ™‚๏ธ Sports Medicine & Rehabilitation โ€“ Non-surgical interventions for orthopedic injuries and performance recovery.

๐Ÿ† Awards & Honors

๐Ÿฅ‡ Overall Winner โ€“ 2024 American Academy of Orthopedic Medicine Annual Scientific Conference

๐Ÿ“š Selected Publications

Mulvaney SW, Lynch JH, Mahadevan S, Dineen K, Rae Olmsted KL. The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Symptom Clusters for Traumatic Brain Injury. Brain Sci. (2024, 14, 1193)

Mulvaney SW, Lynch JH, Rae-Olmstead K, Mahadevan S, Dineen KJ. The Successful Use of Bilateral Two-Level Ultrasound-Guided Stellate Ganglion Block to Improve Traumatic Brain Injury Symptoms. Military Medicine (2024)

Mulvaney SW, Mahadevan S, Dineen KJ, Desronvilles R Jr., Olmsted KLR. Long-Term Durability of Bilateral Two-Level Stellate Ganglion Blocks in PTSD: A Six-Month Retrospective Analysis. Clinical and Translational Neuroscience (2025); 9(1):7

Siddiqui, I. J., Ritner, A., Mahadevan, S., Dineen, K. J., & Desronvilles, R. Regeneration of Full Thickness Common Extensor Tendon Tear after Percutaneous Microfragmented Adipose Graft. Regenerative Medicine (2024)

Siddiqui, I., Probst, J., Mahadevan, S., Desronvilles, R., & Dineen, K. Treating External Anal Sphincter Injury with Platelet-Rich Plasma for Postpartum Fecal Incontinence. J Case Rep Images Obstet Gynecol (2025); 11(1), 22โ€“28