Achievements🏆
- 🔬 Developed pioneering ‘smart diagnostic’ technologies.🏆 Received the 2016 AACC Wallace H. Coulter Lectureship Award.
🌟 Honored with the Kathleen C. Kinnally Outstanding Scientific Achievement Award.
🎖️ Recognized by Popular Science with the Best of What’s New Award in Medical Devices.
🏅 Received the Presidential Young Investigator Award.
📈 Elevated the field with over 219 peer-reviewed publications and 145 patents.
💡 Founded multiple diagnostic companies, including OraLiva, advancing clinical diagnostics.
💰 Raised over $47M in federal and foundation funding for research.
🌐 Contributed to global health initiatives like HIV monitoring in Africa.
🎓 Distinguished career spanning leadership roles at Rice University and NYU, shaping the future of bioengineering and biomaterials.
Projects💧🔬
- 🔬 Point-of-Care Oncology Tool: Developed the first point-of-care oncology tool for precision medicine to monitor malignant transitions and recurrence in patients with oral epithelial dysplasia and prior oral cavity cancers.🧪 Lab-on-a-Chip System for Saliva-Based Diagnostics: Created a groundbreaking lab-on-a-chip system for saliva-based diagnostics aimed at cardiac disease, integrating 17 protein biomarkers for effective diagnosis.
🦷 Monitoring Oral Cancer Patients: Led a project using novel lab-on-a-chip ensembles to monitor oral cancer patients, identifying cellular markers crucial for early detection and treatment.
🔍 Texas Cancer Diagnostics Pipeline Consortium: Spearheaded multiple initiatives under this consortium focusing on oral, ovarian, and prostate cancers, employing advanced bio-nanochips to enhance diagnostic accuracy.
🚔 Saliva-Based Drug Test at Point of Arrest: Designed bio-nanochips for saliva-based drug tests used at the point of arrest, aiding in the detection of drugs and metabolites efficiently.
Publications 📚
📚 Current developments in salivary diagnostics
- Authors: CS Miller, JD Foley, AL Bailey, CL Campell, RL Humphries, …
- Journal: Biomarkers in Medicine
- Volume: 4
- Issue: 1
- Pages: 171-189
- Citations: 509
- Year: 2010
🔬 Aptamer-based sensor arrays for the detection and quantitation of proteins
- Authors: R Kirby, EJ Cho, B Gehrke, T Bayer, YS Park, DP Neikirk, JT McDevitt, …
- Journal: Analytical Chemistry
- Volume: 76
- Issue: 14
- Pages: 4066-4075
- Citations: 402
- Year: 2004
🔍 Application of microchip assay system for the measurement of C-reactive protein in human saliva
- Authors: N Christodoulides, S Mohanty, CS Miller, MC Langub, PN Floriano, …
- Journal: Lab on a Chip
- Volume: 5
- Issue: 3
- Pages: 261-269
- Citations: 316
- Year: 2005
👅 Solution-based analysis of multiple analytes by a sensor array: toward the development of an “electronic tongue”
- Authors: JJ Lavigne, S Savoy, MB Clevenger, JE Ritchie, B McDoniel, SJ Yoo, …
- Journal: Journal of the American Chemical Society
- Volume: 120
- Issue: 25
- Pages: 6429-6430
- Citations: 295
- Year: 1998
🔬 Detection system based on an analyte reactive particle
- Authors: JT McDevitt, EV Anslyn, JB Shear, DP Neikirk
- Publication: US Patent 6,602,702
- Citations: 289
- Year: 2003
🌟 Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels
- Authors: JV Jokerst, A Raamanathan, N Christodoulides, PN Floriano, AA Pollard, …
- Journal: Biosensors and Bioelectronics
- Volume: 24
- Issue: 12
- Pages: 3622-3629
- Citations: 283
- Year: 2009
🩺 A microchip CD4 counting method for HIV monitoring in resource-poor settings
- Authors: WR Rodriguez, N Christodoulides, PN Floriano, S Graham, S Mohanty, …
- Journal: PLoS Medicine
- Volume: 2
- Issue: 7
- Pages: e182
- Citations: 272
- Year: 2005
🔬 Development of multianalyte sensor arrays composed of chemically derivatized polymeric microspheres localized in micromachined cavities
- Authors: A Goodey, JJ Lavigne, SM Savoy, MD Rodriguez, T Curey, A Tsao, …
- Journal: Journal of the American Chemical Society
- Volume: 123
- Issue: 11
- Pages: 2559-2570
- Citations: 260
- Year: 2001
💡 Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study
- Authors: PN Floriano, N Christodoulides, CS Miller, JL Ebersole, J Spertus, …
- Journal: Clinical Chemistry
- Volume: 55
- Issue: 8
- Pages: 1530-1538
- Citations: 256
- Year: 2009
🧬 Differential receptors create patterns diagnostic for ATP and GTP
- Authors: SC McCleskey, MJ Griffin, SE Schneider, JT McDevitt, EV Anslyn
- Journal: Journal of the American Chemical Society
- Volume: 125
- Issue: 5
- Pages: 1114-1115
- Citations: 245
- Year: 2003
🔬 A microchip-based multianalyte assay system for the assessment of cardiac risk
- Authors: N Christodoulides, M Tran, PN Floriano, M Rodriguez, A Goodey, M Ali, …
- Journal: Analytical Chemistry
- Volume: 74
- Issue: 13
- Pages: 3030-3036
- Citations: 229
- Year: 2002
🎨 Self-assembly of conjugated polymers at the air/water interface. Structure and properties of Langmuir and Langmuir− Blodgett films of amphiphilic regioregular polythiophenes
- Authors: N Reitzel, DR Greve, K Kjaer, PB Howes, M Jayaraman, S Savoy, …
- Journal: Journal of the American Chemical Society
- Volume: 122
- Issue: 24
- Pages: 5788-5800
- Citations: 223
- Year: 2000
🛠️ Method and apparatus for the delivery of samples to a chemical sensor array
- Authors: JT McDevitt, EV Anslyn, JB Shear, DP Neikirk
- Publication: US Patent 6,713,298
- Citations: 212
- Year: 2004
🔧 Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
- Authors: JT McDevitt, K Ballard, NJ Christodoulides, PN Floriano, GW Simmons
- Publication: US Patent App. 11/993,705
- Citations: 203
- Year: 2010
🧪 Boronic acid based peptidic receptors for pattern-based saccharide sensing in neutral aqueous media, an application in real-life samples
- Authors: NY Edwards, TW Sager, JT McDevitt, EV Anslyn
- Journal: Journal of the American Chemical Society
- Volume: 129
- Issue: 44
- Pages: 13575-13583
- Citations: 203
- Year: 2007