Tewin Tencomnao | Immunology | Best Researcher Award

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Assist. Prof. Dr. Tewin Tencomnao | Immunology | Best Researcher Award

Dean at Chulalongkorn University, Thailand

Assist. Prof. Dr. Tewin Tencomnao is the Head of the Center of Excellence on Natural Products for Neuroprotection and Anti-Ageing at Chulalongkorn University, where he also serves as Assistant Professor in Clinical Chemistry and Dean of the Faculty of Allied Health Sciences. He holds a Ph.D. in Biochemistry and Molecular Biophysics from Virginia Commonwealth University and a B.Sc. in Medical Technology (Honors) from Chulalongkorn University. His research spans drug discovery, natural products, molecular biology, biochemistry, neuroscience, anti-ageing, and mechanisms of neuropsychiatric diseases. Dr. Tencomnao has authored more than 205 publications, accumulating over 10,636 citations, and maintains a strong h-index of 34, reflecting his influence in neuroprotection and natural product research. He has received several prestigious recognitions, including the 2021 Fulbright Thai Visiting Scholar Award (University of Kentucky), the 2020 Outstanding Researcher Award of Chulalongkorn University, the 2015 DMSc Award from the Ministry of Public Health for his groundbreaking work on Rhinacanthus nasutus, and a 2015 international Gold Award for innovation for developing an anti-ageing cream derived from natural resveratrol. He has contributed extensively to scientific literature through numerous book chapters covering medicinal Thai herbs, neuroprotection, phytochemistry, natural anti-ageing compounds, probiotics, and medicinal plant responses to environmental stresses, with recent works published by CRC Press, Taylor & Francis, Elsevier, Springer Nature, and Bentham Science. His scholarly outputs highlight significant advances in natural neuroprotectants, autophagy regulation, medicinal plant proteomics, anti-glutamate neurotoxicity mechanisms, and therapeutic potentials of phytochemicals in ageing and neurodegeneration, establishing him as a leading authority in natural product-based biomedical innovation.

Profiles: Scopus | Orcid | Google Scholar

Featured Publications

Areekul, P., Bhunyakarnjanarat, T., Suebnuson, S., Somsri, K., Trakultritrung, S., Taveethavornsawat, K., Tencomnao, T., Boonyasuppayakorn, S., & Leelahavanichkul, A. (2025). Less severe inflammation in cyclic GMP–AMP synthase (cGAS)-deficient mice with rabies: Impact of mitochondrial injury and gut–brain axis. Biology, 14(11), 1583. https://doi.org/10.3390/biology14111583

Alugoju, P., Palanisamy, C. P., Anthikapalli, N. V. A., Jayaraman, S., Prasanskulab, A., Chuchawankul, S., Dyavaiah, M., & Tencomnao, T. (2024). Exploring the anti-aging potential of natural products and plant extracts in budding yeast Saccharomyces cerevisiae: A review. F1000Research, 13, 141669. https://doi.org/10.12688/f1000research.141669.2

Alugoju, P., Bhandare, V. V., Patil, V. S., Krishna Swamy, V. K. D., Borugadda, P. K., & Tencomnao, T. (2024). In silico molecular docking and molecular dynamic simulation of agarwood compounds with molecular targets of Alzheimer’s disease. F1000Research, 13, 130618. https://doi.org/10.12688/f1000research.130618.2

Janpaijit, S., Sukprasansap, M., Tencomnao, T., & Prasansuklab, A. (2024). Anti-neuroinflammatory potential of areca nut extract and its bioactive compounds in anthracene-induced BV-2 microglial cell activation. Nutrients, 16(17), 2882. https://doi.org/10.3390/nu16172882

Pattarachotanant, N., Sukjamnong, S., Rangsinth, P., Chaikhong, K., Sillapachaiyaporn, C., Leung, G. P.-H., Hu, V. W., Sarachana, T., Chuchawankul, S., Tencomnao, T., et al. (2024). Aquilaria crassna extract exerts neuroprotective effect against benzo[a]pyrene-induced toxicity in human SH-SY5Y cells: An RNA-seq-based transcriptome analysis. Nutrients, 16(16), 2727. https://doi.org/10.3390/nu16162727

Sharika, R., Mongkolpobsin, K., Rangsinth, P., Prasanth, M. I., Nilkhet, S., Pradniwat, P., Tencomnao, T., & Chuchawankul, S. (2024). Experimental models in unraveling the biological mechanisms of mushroom-derived bioactives against aging- and lifestyle-related diseases: A review. Nutrients, 16(16), 2682. https://doi.org/10.3390/nu16162682

Tedasen, A., Chiabchalard, A., Tencomnao, T., Yamasaki, K., Majima, H. J., Phongphithakchai, A., & Chatatikun, M. (2024). Anti-melanogenic activity of ethanolic extract from Garcinia atroviridis fruits using in vitro experiments, network pharmacology, molecular docking, and molecular dynamics simulation. Antioxidants, 13(6), 713. https://doi.org/10.3390/antiox13060713

Marcella Reale | Infiammazione | Excellence in Research Award

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Prof. Marcella Reale | Infiammazione | Excellence in Research Award

Prof. Marcella Reale | Università “G.d’Annunzio” CHieti-Pescara | Italy

Prof. Marcella Reale is an eminent Italian scientist and Associate Professor of General Pathology at the University “G. d’Annunzio” of Chieti-Pescara, with a Ph.D. in Experimental Medicine from the University “La Sapienza” of Rome and a Degree in Biological Sciences from the University of Bologna. Her distinguished academic career spans research, teaching, and scientific leadership in the fields of immunology, inflammation, and neurodegenerative diseases. Since joining the Faculty of Medicine at “G. d’Annunzio,” she has held numerous institutional roles, including membership in didactic and evaluation commissions, coordination of laboratory programs, and supervision of Ph.D. students in Biomolecular and Pharmaceutical Sciences. Prof. Reale’s research focuses on elucidating molecular and cellular mechanisms of inflammation, the immune response, and their pharmacological regulation, particularly in neurological and systemic diseases. Her studies have examined cytokine production, neuroinflammation, and cholinergic modulation in disorders such as Alzheimer’s disease, multiple sclerosis, and traumatic brain injury. She has also collaborated extensively with international research groups, notably with the National Institute on Aging (NIH, USA), King Abdulaziz University (Saudi Arabia), and University Medicine Berlin, resulting in numerous influential publications. Prof. Reale has authored and co-authored over 245 scientific documents indexed in Scopus, which have collectively received more than 7,410 citations across 6,148 citing documents, achieving an h-index of 46, reflecting her sustained global research impact. She serves on editorial boards of several leading journals, including Frontiers in Immunology, Frontiers in Neurology, and International Journal of Molecular Sciences, and is Editor-in-Chief of AIMS Allergy and Immunology. Her leadership as guest editor for multiple special issues and reviewer for over 70 international journals underscores her reputation as a leading figure in immunopathology and translational medicine. Through her work, Prof. Reale continues to advance knowledge on the interplay between the immune system, inflammation, and neurodegeneration, shaping innovative therapeutic strategies and contributing profoundly to biomedical research.

Profiles:  Scopus | Orcid | Google Scholar 

Featured Publications

Costantini, E., Aielli, L., Gualdi, G., Baronio, M., Monari, P., Amerio, P., & Reale, M. Pulsed radiofrequency electromagnetic fields as modulators of inflammation and wound healing in primary dermal fibroblasts of ulcers. Bioengineering, 11(4), 357.

Reale, M., Borlongan, C., Carta, A. R., & Greig, N. H. Genetic and molecular regulations of neuronal activity. International Journal of Molecular Sciences, 24(22), 16191.

Kopp, K. O., Greer, M. E., Glotfelty, E. J., Hsueh, S.-C., Tweedie, D., Kim, D. S., Reale, M., Vargesson, N., & Greig, N. H. A new generation of IMiDs as treatments for neuroinflammatory and neurodegenerative disorders. Biomolecules, 13(5), 747.

Costantini, E., Di Nicola, M., Marchioni, M., Aielli, L., Reale, M., & Schips, L. Effects of curcumin and lactoferrin to inhibit the growth and migration of prostatic cancer cells. International Journal of Environmental Research and Public Health, 19(23), 16193.

Reale, M., Costantini, E., Aielli, L., Di Giuseppe, F., Angelucci, S., Kamal, M. A., & Greig, N. H. Proteomic signature and mRNA expression in hippocampus of SAMP8 and SAMR1 mice during aging. International Journal of Molecular Sciences, 23(23), 15097.

Costantini, E., Marconi, G. D., Fonticoli, L., Aielli, L., Trubiani, O., Soundara Rajan, T., Pizzicannella, J., Reale, M., & Diomede, F. Improved osteogenic differentiation by extremely low electromagnetic field exposure: Possible application for bone engineering. Histochemistry and Cell Biology, 158(5), 427–440.

Marinelli, L., Cacciatore, I., Costantini, E., Dimmito, M. P., Serra, F., Di Stefano, A., & Reale, M. Wound-healing promotion and anti-inflammatory properties of carvacrol prodrugs/hyaluronic acid formulations. Pharmaceutics, 14(7), 1468.

Costantini, E., Aielli, L., Serra, F., De Dominicis, L., Falasca, K., Di Giovanni, P., & Reale, M. Evaluation of cell migration and cytokines expression changes under the radiofrequency electromagnetic field on wound healing in vitro model. International Journal of Molecular Sciences, 23(4), 2205.