Assoc. Prof. Dr. Jessica Fleming | Molecular Biomarkers | Best Researcher Award

Assoc. Prof. Dr. Jessica Fleming | Molecular Biomarkers | Best Researcher Award

The Ohio State University, United States.

Dr. Jessica L. Fleming, PhD, is an accomplished radiobiologist at the James Comprehensive Cancer Center, The Ohio State University. With over a decade of experience in translational oncology research, she specializes in molecular biomarkers and radiation therapy innovations. Dr. Fleming plays a key role in collaborative clinical and research initiatives, especially in glioma and FLASH radiotherapy. She is also a co-founder and former CEO of the Cap City Biohackers, demonstrating her entrepreneurial edge in biomedical innovation.

Profile

Scopus

🎓 Education

Dr. Fleming earned her PhD in Molecular, Cellular, and Developmental Biology from The Ohio State University in 2012, following a BS in Biology, Cum Laude, from Ashland University in 2006. Her strong academic foundation was supported by multiple fellowships and research opportunities during her undergraduate and graduate studies.

🧪 Experience

Dr. Fleming currently serves as an Associate Radiobiologist at OSU, working with Dr. Arnab Chakravarti. Her journey at OSU began as a graduate student, advancing through postdoctoral research and senior research associate roles. She has led cutting-edge radiobiological studies and was integral to several major clinical protocols. Beyond academia, she was the CEO and Co-Founder of Cap City Biohackers, reflecting her commitment to science outreach and innovation.

🔬 Research Interests

Radiation oncology and molecular oncology, particularly adult gliomas and biomarkers

FLASH radiotherapy, clinical translation, and toxicity modeling

Tumor heterogeneity and resistance mechanisms

Translational research bridging lab discoveries and patient care

🏆 Awards & Honors

🥇 2024 ASTRO Annual Meeting Abstract Award

🏅 Columbus CEO Future 50 Award (2020)

🎖 Best of ASTRO & Basic/Translational Science Abstract Award (2018)

🎓 Alumni Grants for Graduate Research (2012)

🧬 NSF REU Fellow (2005)

🌟 Track & Field Athletic Scholar and Presidential Scholar (2002–2006)

📚 Selected Publications

Here are some of Dr. Fleming’s key publications, with citation and access details:

Fleming JL et al. (2025)Comprehensive Molecular Analysis in NRG Oncology/RTOG 9813Int J Radiat Oncol Biol Phys (Accepted)

Manring HR, Fleming JL et al. (2025)FLASH Radiotherapy: From In Vivo Data to Clinical TranslationHematol Oncol Clin N Am (PMID: 39828472)

Fleming JL, Chakravarti A. (2025)Molecular Biomarkers in Adult Lower-Grade GliomasCancer J, 31(1): e0758. (PMID: 39841423)
Cited by: 2 articles

Kotecha R, Schiff D, Chakravarti A, Fleming JL et al. (2024)Management of IDH-Mutated GliomasJ Clin Oncol, 42(21): 2588-2598. (PMID: 38833641)
Cited by: 15 articles

Becker AP, Becker V, McElroy J, Fleming J et al. (2024)HMGB2 as Biomarker in AstrocytomasCancers (Basel), 16(8): 1516. (PMID: 38672598)
Cited by: 7 articles

Dr. Alaa Sayed | Cardiovascular Medicine | Best Researcher Award

Dr. Alaa Sayed | Cardiovascular Medicine | Best Researcher Award

UPMC, United States.

Alaa A. Sayed is a dedicated physician and researcher specializing in internal medicine and regenerative medicine. Currently serving as the Chief Resident in Internal Medicine at UPMC Mercy Hospital in Pittsburgh, Pennsylvania, Alaa's career spans significant roles across clinical practice, research, and global health initiatives. Her work at institutions like the University of Pittsburgh and the World Health Organization reflects her commitment to patient safety and medical innovation.

Profile

Orcid

Google Scholar

Education 🎓

Alaa earned her MBBCh with honors from Beni Suef University, Egypt, demonstrating her early commitment to medical excellence. She further specialized in regenerative medicine by completing a Master’s degree in Novel Therapeutics from Imperial College London. Her research focused on pioneering cardiac stem cell therapies, reflecting her dedication to advancing innovative treatments in cardiovascular health.

Experience 💼

Alaa brings a wealth of experience across various medical and research roles. She served as an Internal Medicine Chief Resident at UPMC Mercy Hospital, where she honed her clinical leadership skills. At the McGowan Institute for Regenerative Medicine, she contributed as a Research Fellow, deepening her expertise in regenerative therapies. Her career also includes a tenure as a Visiting Research Scholar at the University of Missouri and work as a Quality and Patient Safety Consultant with the World Health Organization. Alaa’s dedication to community health is evident in her role as a Primary Care Physician with the Egyptian Ministry of Health.

Research Interests 🔬

Research Specializations: Regenerative Medicine, Patient Safety, and Quality Care
Alaa’s research is deeply rooted in advancing regenerative medicine, particularly focusing on patient safety and quality care. Her work emphasizes the potential of stem cell therapies, striving to bridge the gap between innovative treatments and effective clinical practices.

Technical Expertise: Dry and Wet Lab Techniques
Alaa is highly skilled in both dry and wet lab methodologies, with extensive experience in cultivating and manipulating stem cell cultures. Her technical acumen extends to bioinformatics and AI-driven analysis, where she applies advanced algorithms to enhance diagnostic and therapeutic outcomes.

AI in Healthcare: Deep Learning and Performance Validation
Alaa’s work frequently intersects with thematic analysis and the validation of deep learning models tailored for healthcare. Her research aims to optimize performance metrics of AI applications, ensuring accurate, reliable, and patient-centered results.

Awards 🏆  

Alaa has been recognized for her excellence in patient safety research, and her contributions have been honored by organizations like the WHO and UPMC.

Her awards reflect her impact on improving patient care and advancing medical research.

Publications Top Notes 📚

Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis
Authors: A. Elgebaly, I. A. I. Radwan, M. M. AboElnas, H. H. Ibrahim, M. F. M. Eltoomy,
Journal: Journal of Gastrointestinal & Liver Diseases, 26(1), 2017. Citations: 89. Link

Functional Microvascularization of Human Myocardium In Vitro
Authors: O. King, D. Cruz-Moreira, A. Sayed, F. Kermani, W. Kit-Anan, I. Sunyovszki,
Journal: Cell Reports Methods, 2(9), 2022. Citations: 24. Link

Implementation Research on Measuring Quality in Primary Care: Balancing National Needs with Learning from the Eastern Mediterranean Region
Authors: M. Letaief, L. R. Hirschhorn, S. Leatherman, A. A. Sayed, A. Sheikh, S. Siddiqi
Journal: International Journal for Quality in Health Care, 33(3), mzab119, 2021. Citations: 7. Link

Vascularized Myocardium-On-A-Chip: Excitation-Contraction Coupling in Perfused Cardiac Co-Cultures
Authors: O. King, D. Cruz-Moreira, S. W. Kit-Anan, A. Sayed, B. Wang, J. Fourre,
Journal: Biophysical Journal, 118(3), 410a, 2020. Citations: 2. Link

Long-Term Association of Low-Density Lipoprotein Subtypes with Coronary Artery Calcium Score and Atherosclerotic Cardiovascular Disease Events: Insights from HeartSCORE Study
Authors: A. Sayed, J. Swanson, K. Kip, E. K. Jesrani, S. Reis, A. Saeed
Journal: Journal of Clinical Lipidology. Link