Assoc. Prof. Dr. Jessica Fleming | Molecular Biomarkers | Best Researcher Award

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Assoc. Prof. Dr. Jessica Fleming | Molecular Biomarkers | Best Researcher Award

The Ohio State University, United States.

Dr. Jessica L. Fleming, PhD, is an accomplished radiobiologist at the James Comprehensive Cancer Center, The Ohio State University. With over a decade of experience in translational oncology research, she specializes in molecular biomarkers and radiation therapy innovations. Dr. Fleming plays a key role in collaborative clinical and research initiatives, especially in glioma and FLASH radiotherapy. She is also a co-founder and former CEO of the Cap City Biohackers, demonstrating her entrepreneurial edge in biomedical innovation.

Profile

Scopus

🎓 Education

Dr. Fleming earned her PhD in Molecular, Cellular, and Developmental Biology from The Ohio State University in 2012, following a BS in Biology, Cum Laude, from Ashland University in 2006. Her strong academic foundation was supported by multiple fellowships and research opportunities during her undergraduate and graduate studies.

🧪 Experience

Dr. Fleming currently serves as an Associate Radiobiologist at OSU, working with Dr. Arnab Chakravarti. Her journey at OSU began as a graduate student, advancing through postdoctoral research and senior research associate roles. She has led cutting-edge radiobiological studies and was integral to several major clinical protocols. Beyond academia, she was the CEO and Co-Founder of Cap City Biohackers, reflecting her commitment to science outreach and innovation.

🔬 Research Interests

Radiation oncology and molecular oncology, particularly adult gliomas and biomarkers

FLASH radiotherapy, clinical translation, and toxicity modeling

Tumor heterogeneity and resistance mechanisms

Translational research bridging lab discoveries and patient care

🏆 Awards & Honors

🥇 2024 ASTRO Annual Meeting Abstract Award

🏅 Columbus CEO Future 50 Award (2020)

🎖 Best of ASTRO & Basic/Translational Science Abstract Award (2018)

🎓 Alumni Grants for Graduate Research (2012)

🧬 NSF REU Fellow (2005)

🌟 Track & Field Athletic Scholar and Presidential Scholar (2002–2006)

📚 Selected Publications

Here are some of Dr. Fleming’s key publications, with citation and access details:

Fleming JL et al. (2025) – Comprehensive Molecular Analysis in NRG Oncology/RTOG 9813 – Int J Radiat Oncol Biol Phys (Accepted)

Manring HR, Fleming JL et al. (2025) – FLASH Radiotherapy: From In Vivo Data to Clinical Translation – Hematol Oncol Clin N Am (PMID: 39828472)

Fleming JL, Chakravarti A. (2025) – Molecular Biomarkers in Adult Lower-Grade Gliomas – Cancer J, 31(1): e0758. (PMID: 39841423)
➤ Cited by: 2 articles

Kotecha R, Schiff D, Chakravarti A, Fleming JL et al. (2024) – Management of IDH-Mutated Gliomas – J Clin Oncol, 42(21): 2588-2598. (PMID: 38833641)
➤ Cited by: 15 articles

Becker AP, Becker V, McElroy J, Fleming J et al. (2024) – HMGB2 as Biomarker in Astrocytomas – Cancers (Basel), 16(8): 1516. (PMID: 38672598)
➤ Cited by: 7 articles

Prof. Huasong Ai | Chemical Biology | Best Researcher Award

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Prof. Huasong Ai | Chemical Biology | Best Researcher Award

Shanghai Jiao Tong University, China.

Prof. Huasong Ai is an Associate Professor at the School of Pharmaceutical Science, Shanghai Jiao Tong University, China. His research focuses on epigenetic mechanisms, chemical biology, and nucleosome modifications. With a strong background in organic chemistry and pharmacy, he has pioneered innovative methods in histone modification synthesis and chromatin ubiquitination studies. Prof. Ai has published 28 research papers, including 13 as the first or corresponding author in prestigious journals such as Nature Chemical Biology, Molecular Cell, and JACS. He is a recipient of multiple academic honors, including the Tsinghua University Excellent Doctoral Dissertation Award and Innovation Award.

Profile

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🎓 Education

Prof. Huasong Ai earned his Ph.D. in Organic Chemistry from Tsinghua University (2017–2022) under the mentorship of Prof. Lei Liu. His doctoral research focused on epigenetic mechanisms and chemical synthesis of post-translationally modified nucleosomes, contributing to advancements in histone modification studies. Prior to his Ph.D., he completed his Bachelor’s Degree in Pharmacy at Tsinghua University, School of Pharmacy (2013–2017), where he built a strong foundation in pharmaceutical sciences, drug development, and organic chemistry. His academic journey has equipped him with interdisciplinary expertise in chemical biology, molecular mechanisms, and structural biochemistry.

💼 Work Experience

Prof. Huasong Ai is currently an Associate Professor at Shanghai Jiao Tong University, where he leads cutting-edge research in epigenetics, chemical biology, and nucleosome modifications. Prior to this, he served as an Assistant Researcher and Postdoctoral Fellow at Tsinghua University (2022–Present), working under Prof. Lei Liu to develop novel chemical synthesis methods for studying post-translational modifications of histones and chromatin dynamics.

His research experience also includes international collaborations. In 2023, he was a Visiting Scholar at Shanghai Jiao Tong University, where he expanded his work on biochemical and structural mechanisms of epigenetic effectors. Additionally, in 2019, he conducted research as a Visiting Scholar at the University of Chicago, working with Prof. Minglei Zhao on advanced molecular biology techniques to study histone ubiquitination and its role in gene regulation.

🔍 Research Interests

Prof. Ai’s research focuses on epigenetic effectors and post-translational modifications of nucleosomes, particularly in:

🔬 Chemical synthesis of modified histones/nucleosomes

🧬 Chromatin ubiquitination mechanisms

⚛️ Structural and biochemical analysis of epigenetic regulators
His innovative work has led to breakthroughs in histone modification studies and protein regulation mechanisms.

🏆 Awards & Honors

Tsinghua University High-Level Young Talent Program "Shuimu Scholar"

Tsinghua University Excellent Doctoral Dissertation Award 🏅

Three-time recipient of Tsinghua University Postdoctoral Excellence Award 🎖️

China Postdoctoral Science Foundation (Special & General Funding)

Journal Reviewer – Nature Chemical Biology, Nature Structural & Molecular Biology

📚 Selected Publications

1️⃣ The Emerging Role of the Histone H2AK13/15 Ubiquitination: Mechanisms of Writing, Reading, and Erasing in DNA Damage Repair and Disease
📌 Cells, 2025-02-18

2️⃣ Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally Defined K63-Polyubiquitylated Linker Histone H1
📌 Angewandte Chemie International Edition, 2025-01-02

3️⃣ Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally Defined K63-Polyubiquitylated Linker Histone H1
📌 Angewandte Chemie, 2025-01-02

4️⃣ Structural and Mechanistic Basis for Nucleosomal H2AK119 Deubiquitination by Single-Subunit Deubiquitinase USP16
📌 Nature Structural & Molecular Biology, 2024-11

5️⃣ Mechanism of Nucleosomal H2A K13/15 Monoubiquitination and Adjacent Dual Monoubiquitination by RNF168
📌 Nature Chemical Biology, 2024-10-11

 

 

Mr. Xiaogang Liu | Molecular Biology | Best Researcher Award

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Mr. Xiaogang Liu | Molecular Biology | Best Researcher Award

Beijing Institute of Technology, China.

Dr. Xiaogang Liu is a dedicated Lecturer at the Zhuhai Campus of Beijing Institute of Technology. With a strong foundation in Biochemistry and Molecular Biology, he specializes in Chemical Biology. His research primarily focuses on Computational Chemistry to study pH-Responsive Fluorescent Probes and develop related software. In addition to his research contributions, he is passionate about teaching and mentoring students in the areas of Molecular Biology and Immunology.

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Education 🎓

Xiaogang Liu earned his Bachelor’s Degree in Biochemistry from Shanxi University, where he laid the groundwork for his extensive studies in the fields of Biochemistry and Molecular Biology. During his time at Shanxi University, he gained a solid understanding of the core principles of biochemical processes and molecular interactions, which set the stage for his later academic pursuits. His education at Shanxi University sparked his passion for Chemical Biology, ultimately shaping his career in research and teaching.

Experience 💼

Dr. Liu has taken on multiple roles in research and academia. Currently, as a Lecturer at Beijing Institute of Technology, he actively teaches and supervises students while also conducting research in Bioinformatics and Chemical Biology. His work focuses on exploring computational methodologies to understand complex chemical systems and biological molecules.

Research Interests 🔬

Chemical Biology: Investigating pH-Responsive Fluorescent Probes

Computational Chemistry: Developing software to support chemical biology research

Bioinformatics: Exploring the intersection of biology and computing to enhance molecular biology applications
Dr. Liu's research also delves into the integration of Computational Chemistry and Chemical Biology to advance understanding in fields like fluorescence sensing, probe design, and software development.

Selected Publications 📚

Computational Chemistry Study of pH-Responsive Fluorescent Probes and Development of Supporting Software
Journal: Molecules (2025), Volume: 30(2), Article 273
Contributors: Xiaogang Liu

Large Scale Virtual Screening for Finding Inhibitor against the RNA-dependent RNA Polymerase from Herbal Medicine for SARS-Cov-2 Therapy
Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics (2022)
Contributors: Xiaogang Liu, Zirong Liang, Shiye Wu, Ying Wang, Binquan Gou

Virtual Screening for Finding Inhibitor Against the Main Protease of SARS-Cov-2 from the FDA-Approved Drugs Database
International Conference on Biomedical and Intelligent Systems (IC-BIS 2022) (2022-12-06)
Contributors: Xiaogang Liu, Shiye Wu, Zitong Zhu, Ying Wang, Binquan Gou

Teaching Reform and Application of Cell Biology in Bioengineering Specialty
Science & Technology Information (2021-12-13)
Contributors: Xiaogang Liu