Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, China
Cui Chen, an Assistant Researcher at the Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, specializes in the development and regeneration of orofacial bones. With a focus on mesenchymal stem cells and their role in bone remodeling and tooth eruption, Cui has contributed extensively to the understanding of mandibular growth and alveolar bone formation. His impactful research includes high-impact publications and innovative findings in the field of stomatology.
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Education 🎓
Dr. Chen Cui earned his Ph.D. in Stomatology from Sichuan University (2017–2020), where he conducted in-depth research on orofacial bone development and mesenchymal stem cell mechanisms in mandibular growth. Prior to this, he completed his Bachelor of Dental Surgery (BDS) at Sichuan University (2012–2017), gaining a strong foundation in dental sciences and clinical practice. His academic journey has been marked by a commitment to advancing knowledge in stomatology and regenerative dentistry.
Experience 💼
Dr. Chen currently serves as an Assistant Researcher at the Hospital of Stomatology, Sun Yat-Sen University (2020–Present), where he focuses on groundbreaking studies in orofacial bone development and regeneration. Previously, he was a Postdoctoral Research Fellow at the same institution (2020–2022), during which he contributed significantly to projects exploring the molecular and cellular mechanisms underlying bone formation and repair. His roles demonstrate a continuous trajectory of excellence and dedication to advancing dental and craniofacial research.
Research Interests 🔬
Development and Regeneration of Orofacial Bones 🦷
Chen Cui's research delves deeply into the intricate processes of orofacial bone development and regeneration. His work aims to unravel the cellular and molecular pathways that govern the growth, repair, and restoration of craniofacial structures, addressing critical challenges in dental and craniofacial health.
Mechanisms of Mesenchymal Stem Cells in Bone and Tooth Formation 🔬
A significant focus of his studies is on mesenchymal stem cells (MSCs) and their pivotal role in the formation of bones and teeth. By exploring how MSCs contribute to tissue differentiation and regeneration, Chen Cui seeks to enhance therapeutic strategies for bone and dental restoration.
Alveolar Bone Remodeling in Inflammatory Environments 🌟
Chen Cui has investigated the impact of inflammation on alveolar bone remodeling, shedding light on how environmental factors influence bone integrity. His findings offer insights into improving treatment outcomes for conditions like periodontitis and bone loss associated with inflammatory disorders.
The Role of Parathyroid Hormone Signaling in Dental Development 🧬
Exploring the parathyroid hormone (PTH) signaling pathway, Chen Cui has identified its critical role in regulating dental development and tooth eruption. His research on PTH signaling contributes to a deeper understanding of bone health and has implications for treating dental anomalies and diseases.
Awards & Recognitions 🏆
Recipient of the National Natural Science Foundation of China Grant
Funded by the China Postdoctoral Science Foundation
Recognized by the Guangdong Basic and Applied Basic Research Foundation
Publications Top Notes 📚
PTH1R Suppressed Apoptosis of Mesenchymal Progenitors in Mandibular Growth (2024), International Journal of Molecular Sciences. Link
Klotho in Osx+ Mesenchymal Progenitors Exerts Pro-Osteogenic Effects (2022), Signal Transduction and Targeted Therapy. Cited by: 28. Link
Dental Follicle Progenitor/Stem Cells: Mechanisms to Applications (2021), Biomolecules. Cited by: 34. Link
Fibrocartilage Stem Cells in Temporomandibular Joints (2021), Frontiers in Cell and Developmental Biology Cited by: 9. Link
Role of PTH1R Signaling in Prx1+ Mesenchymal Progenitors during Eruption (2020), Journal of Dental Research Cited by: 27. Link